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Endothelial colony forming cell
Endothelial colony forming cells (or ECFCs) are adult endothelial progenitor cells capable of differentiating to regenerate endothelial cell populations. They are residents of adult vasculature and are also thought to migrate to areas of injury as one form of circulating endothelial cell. They are thought to play a critical role in vascular healing after injury as well as developmental angiogenesis.
==Characteristics==
ECFCs are commercially available and phenotypically identified by the positive markers CD34, CD31, VEGFR2, eNOS, CD105, and vWF. They also must test negative for CD133, CD45, CD117, and CD141. ECFCs are named for their ability to form colonies of cells which progress rapidly to capillary-like networks in vitro when cultured in biopolymer matrix, and in vivo.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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